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Title: | Efficient synthesis of a new pipecolic acid analogue with a bicyclic structure |
Authors: | Casabona, Diego; Cativiela, Carlos CSIC ORCID | Keywords: | Constrained amino acid Quaternary amino acid Proline analogues 2,5-Ethanepipecolic acid Chemoselective reduction |
Issue Date: | 16-Oct-2006 | Publisher: | Elsevier | Citation: | Tetrahedron 62(42): 10000-10004 (2006) | Abstract: | This report describes the synthesis of 2-azabicyclo[2.2.2]octane-1-carboxylic acid, a constrained pipecolic acid analogue. The route gives a very good total yield starting from cheap and readily available compounds and uses very easy reactions. | Description: | 5 pages, 3 figures, scheme 1. | Publisher version (URL): | http://dx.doi.org/10.1016/j.tet.2006.08.006 | URI: | http://hdl.handle.net/10261/19413 | DOI: | 10.1016/j.tet.2006.08.006 | ISSN: | 0098-1354 |
Appears in Collections: | (ICMA) Artículos |
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