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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/19413
Title: Efficient synthesis of a new pipecolic acid analogue with a bicyclic structure
Authors: Casabona, Diego; Cativiela, Carlos
Keywords: Constrained amino acid
Quaternary amino acid
Proline analogue
2,5-Ethanepipecolic acid
Chemoselective reduction
Issue Date: 16-Oct-2006
Publisher: Elsevier
Citation: Tetrahedron 62(42): 10000-10004 (2006)
Abstract: This report describes the synthesis of 2-azabicyclo[2.2.2]octane-1-carboxylic acid, a constrained pipecolic acid analogue. The route gives a very good total yield starting from cheap and readily available compounds and uses very easy reactions.
Description: 5 pages, 3 figures, scheme 1.
Publisher version (URL): http://dx.doi.org/10.1016/j.tet.2006.08.006
URI: http://hdl.handle.net/10261/19413
DOI: 10.1016/j.tet.2006.08.006
ISSN: 0098-1354
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