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Closed Access item Efficient synthesis of a new pipecolic acid analogue with a bicyclic structure

Authors:Casabona, Diego
Cativiela, Carlos
Keywords:Constrained amino acid, Quaternary amino acid, Proline analogue, 2,5-Ethanepipecolic acid, Chemoselective reduction
Issue Date:16-Oct-2006
Publisher:Elsevier
Citation:Tetrahedron 62(42): 10000-10004 (2006)
Abstract:This report describes the synthesis of 2-azabicyclo[2.2.2]octane-1-carboxylic acid, a constrained pipecolic acid analogue. The route gives a very good total yield starting from cheap and readily available compounds and uses very easy reactions.
Description:5 pages, 3 figures, scheme 1.
Publisher version (URL):http://dx.doi.org/10.1016/j.tet.2006.08.006
URI:http://hdl.handle.net/10261/19413
ISSN:0098-1354
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Appears in Collections:(ICMA) Artículos

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