Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/18814
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Adsorption of recombinant human bone morphogenetic protein rhBMP-2m onto hydroxyapatite |
Autor: | Boix, T.; Gómez-Morales, Jaime CSIC ORCID ; Torrent-Burgués, J.; Monfort, Amparo CSIC ORCID CVN; Puigdomènech, Pere CSIC | Palabras clave: | RhBMP-2m Hydroxyapatite Adsorption Langmuir isotherm |
Fecha de publicación: | may-2005 | Editor: | Elsevier | Citación: | Journal of Inorganic Biochemistry 99(5): 1043-1050 (2005) | Resumen: | Recombinant human mature bone morphogenetic protein 2 (rhBMP-2m) has been expressed to study its adsorption onto precipitated hydroxyapatite (HA). The influence on the adsorption process of different parameters such as pH and concentrations of calcium, phosphate or NaCl has been investigated. Although the adsorption proceeds rapidly at the initial stages, the maximum adsorbed amount is reached after four hours. The process is notably influenced by adding calcium or phosphate to the system but, while calcium ions increase the adsorption of rhBMP-2m onto HA, phosphate ions inhibit it. The influence of pH and NaCl concentration are notable but less important than those of calcium and phosphate. The adsorption data fit well to a Langmuir adsorption isotherm. The values of the isotherm parameters have been calculated and discussed, and an adsorption mechanism has been proposed. | Descripción: | 8 figures, 2 tables. | Versión del editor: | http://dx.doi.org/10.1016/j.jinorgbio.2005.01.011 | URI: | http://hdl.handle.net/10261/18814 | DOI: | 10.1016/j.jinorgbio.2005.01.011 |
Aparece en las colecciones: | (IACT) Artículos |
Mostrar el registro completo
CORE Recommender
SCOPUSTM
Citations
90
checked on 20-abr-2024
WEB OF SCIENCETM
Citations
82
checked on 24-feb-2024
Page view(s)
435
checked on 23-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.