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Diffusion-weighted magnetic resonance imaging

AuthorsGuadilla, Irene; Calle, Daniel ; López-Larrubia, Pilar
KeywordsMagnetic resonance imaging
Preclinical MRI
Diffusion-weighted imaging
Echo-planar imaging
Apparent diffusion coefficient
Issue Date2018
PublisherSpringer Nature
CitationPreclinical MRI: 89-101 (2018)
SeriesMethods in Molecular Biology 1718
AbstractMagnetic resonance imaging (MRI) is a technique based on the contents and relaxation features of water in tissues. In basic MRI sequences, diffusion phenomenon of water molecules is not taken into account although it has a notable influence in the relaxation times, and therefore in the signal intensity of images. In fact, MRI techniques that take advantage of water diffusion have experienced a huge development in last years. Diffusion-weighted imaging (DWI) has spectacularly evolved reaching nowadays a great impact both in clinical and preclinical imaging—especially in the neuroimaging field—and in basic research. We present here a protocol to perform DWI studies in a high-field preclinical setup.
Publisher version (URL)https://doi.org/10.1007/978-1-4939-7531-0_6
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