Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/185748
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Diezma-Navas, Laura | es_ES |
dc.contributor.author | Pérez-González, Ana | es_ES |
dc.contributor.author | Artaza-Álvarez, Haydeé | es_ES |
dc.contributor.author | Alonso, Lola | es_ES |
dc.contributor.author | Caro, Elena | es_ES |
dc.contributor.author | Llave, César | es_ES |
dc.contributor.author | Ruiz-Ferrer, Virginia | es_ES |
dc.date.accessioned | 2019-07-09T12:22:16Z | - |
dc.date.available | 2019-07-09T12:22:16Z | - |
dc.date.issued | 2019-07-05 | - |
dc.identifier.citation | Molecular plant pathology (2019) | es_ES |
dc.identifier.issn | 1464-6722 | - |
dc.identifier.uri | http://hdl.handle.net/10261/185748 | - |
dc.description | 14 p.-6 fig. | es_ES |
dc.description.abstract | DNA methylation is an important epigenetic mechanism for controlling innate immunity against microbial pathogens in plants. Little is known, however, about the manner in which viral infections interact with DNA methylation pathways. Here we investigate the crosstalk between epigenetic silencing and viral infections in Arabidopsis inflorescences. We found that tobacco rattle virus (TRV) causes changes in the expression of key transcriptional gene silencing factors with RNA‐directed DNA methylation activities that coincide with changes in methylation at the whole genome level. Viral susceptibility/resistance was altered in DNA (de)methylation‐deficient mutants, suggesting that DNA methylation is an important regulatory system controlling TRV proliferation. We further show that several transposable elements (TEs) underwent transcriptional activation during TRV infection, and that TE regulation likely involved both DNA methylation‐dependent and ‐independent mechanisms. We identified a cluster of disease resistance genes regulated by DNA methylation in infected plants that were enriched for TEs in their promoters. Interestingly, TEs and nearby resistance genes were co‐regulated in TRV‐infected DNA (de)methylation mutants. Our study shows that DNA methylation contributes to modulate the outcome of viral infections in Arabidopsis, and opens up new possibilities for exploring the role of TE regulation in antiviral defence. | es_ES |
dc.description.sponsorship | This work has been supported by a Ramon y Cajal grant (RyC‐2011‐07006) to VRF and by National Research grants BIO2012‐39973 and BIO2015‐70752‐R to CL from Ministerio de Economía y Competitividad (MINECO/FEDER), Spain. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | John Wiley & Sons | es_ES |
dc.relation | info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BIO2015-70752-R | es_ES |
dc.relation.isversionof | Publisher's version | es_ES |
dc.rights | openAccess | es_ES |
dc.subject | Arabidopsis thaliana | es_ES |
dc.subject | Disease resistance genes | es_ES |
dc.subject | DNA methylation | es_ES |
dc.subject | Plant–virus interactions | es_ES |
dc.subject | Plant viruses | es_ES |
dc.subject | RNA-dependent DNA methylation | es_ES |
dc.subject | Tobacco rattle virus | es_ES |
dc.subject | Transposable elements | es_ES |
dc.title | Crosstalk between epigenetic silencing and infection by tobacco rattle virus in Arabidopsis | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1111/mpp.12850 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1111/mpp.12850 | es_ES |
dc.identifier.e-issn | 1364-3703 | - |
dc.rights.license | https://creativecommons.org/licenses/by/4.0/ | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.contributor.orcid | Diezma-Navas, Laura [0000-0001-5857-5091] | es_ES |
dc.contributor.orcid | Pérez-González, Ana [0000-0002-7724-9985] | es_ES |
dc.contributor.orcid | Artaza-Álvarez, Haydeé [0000-0002-1585-5488] | es_ES |
dc.contributor.orcid | Alonso, Lola [0000-0002-3493-718X] | es_ES |
dc.contributor.orcid | Caro, Elena [0000-0002-1034-1621] | es_ES |
dc.contributor.orcid | Llave, César [0000-0003-3844-4582] | es_ES |
dc.contributor.orcid | Ruiz-Ferrer, Virginia [0000-0002-7840-297X] | es_ES |
dc.identifier.pmid | 31274236 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (CIB) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
mpp_ruiz-ferrer_2019pdf.pdf | Artículo principal | 1,12 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
10
checked on 19-abr-2024
SCOPUSTM
Citations
23
checked on 23-abr-2024
WEB OF SCIENCETM
Citations
20
checked on 26-feb-2024
Page view(s)
270
checked on 24-abr-2024
Download(s)
178
checked on 24-abr-2024