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Open Access item A synthetic alternative to natural lecithins with antimicrobial properties

Authors:Pérez, Lourdes
Infante, María Rosa
Pons Pons, Ramon
Morán, María del Carmen
Vinardell, M. Pilar
Mitjans, Montserrat
Pinazo Gassol, Aurora
Keywords:Ammino acid arginine, Biocompatible multifunctional surfactants
Issue Date:14-May-2004
Citation:Colloids and Surfaces B Biointerfaces 35(3-4): 235-242 (2004)
Abstract:Two soft biocompatible cationic surfactants from the amino acid arginine, 1,2-dilauroyl-3-acetylarginyl-rac-glycerol (1212RAc) and 1,2-dimirystoyl-3-acetylarginyl-rac-glycerol (1414RAc), were prepared. Their physicochemical properties show that they can be classified as multifunctional surfactants with self-aggregation behaviour comparable to that of short-chain lecithins. The two surfactants can simultaneously stabilise water-in-oil (W/O) droplets and oil-in-water (O/W) droplets, forming multiple emulsions. They have antimicrobial activity similar to that of conventional cationic surfactants and are as harmless as amphoteric betaines. These surfactants constitute an interesting alternative to the diglycerides and lecithins in formulations that require antimicrobial properties.
Description:8 pages, 4 figures, 5 tables.-- PMID: 15261036 [PubMed].-- Printed version published Jun 1, 2004.
Publisher version (URL):http://dx.doi.org/10.1016/j.colsurfb.2004.03.014
ISSN:0927-7765 (Print)
1873-4367 (Online)
Appears in Collections:(IQAC) Artículos

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