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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/18540
Title: A synthetic alternative to natural lecithins with antimicrobial properties
Authors: Pérez, Lourdes; Infante, María Rosa; Pons Pons, Ramón; Morán, María del Carmen; Vinardell, M. Pilar; Mitjans, Montserrat; Pinazo Gassol, Aurora
Keywords: Ammino acid arginine
Biocompatible multifunctional surfactants
Issue Date: 14-May-2004
Publisher: Elsevier
Citation: Colloids and Surfaces B Biointerfaces 35(3-4): 235-242 (2004)
Abstract: Two soft biocompatible cationic surfactants from the amino acid arginine, 1,2-dilauroyl-3-acetylarginyl-rac-glycerol (1212RAc) and 1,2-dimirystoyl-3-acetylarginyl-rac-glycerol (1414RAc), were prepared. Their physicochemical properties show that they can be classified as multifunctional surfactants with self-aggregation behaviour comparable to that of short-chain lecithins. The two surfactants can simultaneously stabilise water-in-oil (W/O) droplets and oil-in-water (O/W) droplets, forming multiple emulsions. They have antimicrobial activity similar to that of conventional cationic surfactants and are as harmless as amphoteric betaines. These surfactants constitute an interesting alternative to the diglycerides and lecithins in formulations that require antimicrobial properties.
Description: 8 pages, 4 figures, 5 tables.-- PMID: 15261036 [PubMed].-- Printed version published Jun 1, 2004.
Publisher version (URL): http://dx.doi.org/10.1016/j.colsurfb.2004.03.014
URI: http://hdl.handle.net/10261/18540
DOI: 10.1016/j.colsurfb.2004.03.014
ISSN: 0927-7765 (Print)
1873-4367 (Online)
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