Compositional study, antibacterial and antioxidant potential of Lepidium draba L. (brascicaceae)

Abstract

The present study was designed to evaluate the phytochemical screening, antimicrobial and antioxidant activities of Lepidium draba The arial parts of Lepidium draba showed the presence of alkaloids, terpenoids, tannins,saponins, Leuco anthocyans, triterpenoids and flavonoids. Three known flavonoid glycosides: rhamnocitrin- 3-O- Dglucoside (1), complanatuside (2), genkwanin- 4’-O- Dglucoside (3) were isolated from the all parts of Lepidium draba their structures were elucidated by NMR experiments and acid hydrolysis. The antibacterial activity of the extracts was evaluated by disc diffusion assay and the antioxidant activity and phenolic contents of n-butanol extract were evaluated in vitro using spectrophotometer methods.