Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/181288
COMPARTIR / EXPORTAR:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE

Invitar a revisión por pares abierta
Título

RGD-Functionalized Fe3O4 nanoparticles for magnetic hyperthermia

AutorArriortua, Oihane K.; Insausti, Maite; Lezama, Luis; Gil de Muro, Izaskun; Garaio, Eneko; Fuente, Jesús M. de la CSIC ORCID; Fratila, Raluca M. CSIC ORCID; Morales, M. P. CSIC ORCID ; Costa, Rocío; Eceiza, Maite; Sagartzazu-Aizpurua, Maialen; Aizpurua, Jesús M.
Palabras claveCitotoxicity
EMR
Hyperthermia
RGD
Magnetite
Fecha de publicación2018
EditorElsevier
CitaciónColloids and Surfaces B: Biointerfaces 165: 315-324 (2018)
ResumenTo improve the selectivity of magnetic nanoparticles for tumor treatment by hyperthermia, Fe3O4 nanoparticles have been functionalized with a peptide of the type arginine-glycine-aspartate (RGD) following a "click" chemistry approach. The RGD peptide was linked onto the previously coated nanoparticles in order to target αvβ3 integrin receptors over-expressed in angiogenic cancer cells. Different coatings have been analyzed to enhance the biocompatibility of magnetic nanoparticles. Monodispersed and homogeneous magnetite nanoparticles have been synthesized by the seed growth method and have been characterized using X-ray diffraction, thermogravimetric analysis, infrared spectroscopy, transmission electron microscopy and magnetic measurements. The magnetic hyperthermia efficiency of the nanoparticles has also been investigated and cytotoxicity assays have been perfomed for functionalized nanoparticles.
Versión del editorhttps://doi.org/10.1016/j.colsurfb.2018.02.031
URIhttp://hdl.handle.net/10261/181288
DOI10.1016/j.colsurfb.2018.02.031
ISSN0927-7765
E-ISSN1873-4367
Aparece en las colecciones: (ICMM) Artículos
(ICMA) Artículos




Ficheros en este ítem:
Fichero Descripción Tamaño Formato
accesoRestringido.pdf59,24 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo

CORE Recommender

PubMed Central
Citations

15
checked on 24-mar-2024

SCOPUSTM   
Citations

50
checked on 22-mar-2024

WEB OF SCIENCETM
Citations

44
checked on 29-feb-2024

Page view(s)

232
checked on 28-mar-2024

Download(s)

43
checked on 28-mar-2024

Google ScholarTM

Check

Altmetric

Altmetric


Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.