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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/18094
Title: Synthesis of the Antioxidant Hydroxytyrosol Using Tyrosinase as Biocatalyst
Authors: Espín de Gea, Juan Carlos; Soler-Rivas, Cristina ; Cantos Villar, Emma; Tomás Barberán, Francisco; Wichers, Harry J.
Keywords: Enzymatic synthesis
Olive oil
Vegetative waters
Issue Date: 10-Feb-2001
Publisher: American Chemical Society
Citation: Journal of Agricultural and Food Chemistry 49(3): 1187-1193 (2001)
Abstract: Hydroxytyrosol (HTyr), a natural ortho-diphenolic antioxidant with health-beneficial properties that mainly occurs in virgin olive oil and olive oil mill waste waters (also known as vegetative waters), has been enzymatically synthesized using mushroom tyrosinase. This o-diphenol (not commercially available) was obtained from its monophenolic precursor tyrosol (commercially available) in the presence of both tyrosinase and ascorbic acid. The reaction synthesis is continuous, easy to perform, and adaptable to a bioreactor for industrial purposes. The HTyr concentration is time-predicted, and the yield of reaction can be 100%. The synthesis method reported here is an alternative approach to obtain this compound in an environmentally friendly way.
Description: 7 pages, 6 figures.
Publisher version (URL): http://dx.doi.org/10.1021/jf001258b
URI: http://hdl.handle.net/10261/18094
DOI: 10.1021/jf001258b
ISSN: 1520-5118 (Online)
0021-8561 (Print)
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