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Título: | In vitro method for identifying thoracic aortic aneurysms (taa) in a subject |
Autor: | Redondo, Juan Miguel CSIC ORCID; Méndez-Barbero, Nerea; Oller, Jorge; Campanero, Miguel R. CSIC ORCID | Fecha de publicación: | 14-sep-2017 | Citación: | WO2017153023 A1 | Resumen: | The present invention refers to an In vitro method for screening for subjects at risk of developing thoracic aortic aneurysm (TAA) or a disease causing TAA comprising: (a) measuring the expression pattern or level of at least A Disintegrin And Metalloproteinase with Thrombospondin Motifs 1 (ADAMTS1) obtained from an isolated biological sample of the subjects to be screened; and (b) comparing said expression pattern or level of at least ADAMTS1 of the subjects to be screened with an already established expression pattern or level, wherein reduced expression of at least ADAMTS1 is indicative of a thoracic aortic aneurysm (TAA). | URI: | http://hdl.handle.net/10261/180584 |
Aparece en las colecciones: | (CIC) Patentes (IIBM) Patentes |
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WO2017153023A1.pdf | 15,22 MB | Adobe PDF | Visualizar/Abrir |
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