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Compositions comprising composite nanocarriers and methods of making and uses thereof

AuthorsKorgel, Brian A.; Silbaugh, Dorothy A.; Ventosa, Nora ; Ferrer Tasies, Lidia P. ; Veciana, Jaume
Issue Date31-Aug-2017
CitationWO2017147407 A1
AbstractDisclosed herein are compositions comprising an aqueous solution comprising a composite nanocarrier, the composite nanocarrier comprising a nanoparticle at least partially encapsulated within a vesicle, the vesicle comprising a sterol and a surfactant. In some examples, the vesicle consists of a sterol and a surfactant. In some examples, the sterol comprises cholesterol or a derivative thereof. In some examples, the surfactant comprises a quaternary ammonium surfactant, such as cetyl trimethylammonium bromide. In some examples, the nanoparticle comprises Si. The compositions described herein can be substantially stable. Also disclosed herein are methods of making and methods of use of the composition disclosed herein.
Appears in Collections:(ICMAB) Patentes
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