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EvalMSA: A Program to Evaluate Multiple Sequence Alignments and Detect Outliers

AuthorsChiner-Oms, Álvaro ; González-Candelas, Fernando
Multiple sequence alignment
Outlier sequence
Issue Date28-Nov-2016
PublisherLibertas Académica
CitationEvolutionary Bioinformatics 12:277-284 (2016)
AbstractWe present EvalMSA, a software tool for evaluating and detecting outliers in multiple sequence alignments (MSAs). This tool allows the identification of divergent sequences in MSAs by scoring the contribution of each row in the alignment to its quality using a sum-of-pair-based method and additional analyses. Our main goal is to provide users with objective data in order to take informed decisions about the relevance and/or pertinence of including/retaining a particular sequence in an MSA. EvalMSA is written in standard Perl and also uses some routines from the statistical language R. Therefore, it is necessary to install the R-base package in order to get full functionality. Binary packages are freely available from http://sourceforge.net/projects/evalmsa/for Linux and Windows.
Description8 páginas, 3 figuras, 2 tablas.
Publisher version (URL)http://dx.doi.org/10.4137/EBO.S40583
Appears in Collections:(IBV) Artículos
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