English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/179250
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


New Synthetic Strategies Based on C-, O- and N-centered Radicals

AuthorsMartín, Ángeles ; Herrera, Antonio J.
Issue Date6-May-2013
CitationCOST Action CM1201. 2nd MC meeting & 1st Annual Scientific Meeting (2013)
AbstractOur last research programs have been based on the development of new selective and environmentally friendly synthetic methodologies for the synthesis of chiral synthons and novel bioactive compounds. We have introduced the use of new oxidizing systems based on hypervalent iodine reagents for the generation of O- and N-centered radicals and the use of visible light or sunlight to generate C-radical by photoexcitation of 1,2- diketones. These protocols provide challenging ways to perform chemical modifications on carbohydrates and amino acids, affording a wide variety of substructures present in natural products and their analogues, as well as enable to study the behavior of transient radicals postulated in biological processes such as DNA damage. In this talk, we will show an overview of our main research lines, focused on the application of different kind of reactions and reactive species, including Hydrogen Atom Transfer (HAT) reactions promoted by O- and N-centered radicals, β-fragmentation reactions of O-centered radicals, and HAT reactions of photoexcited 1,2-diketones.
DescriptionTrabajo presentado en el 2nd MC meeting & 1st Annual Scientific Meeting (COST Action CM1201) celebrado en Bolonia (Italia) del 5 al 7 de mayo de 2013.
Appears in Collections:(IPNA) Comunicaciones congresos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.