English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/177611
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Chronic pain and cannabinoids. Great expectations or a christmas carol

AuthorsPascual, D.; Sánchez-Robles, E. M.; García, M. M.; Goicoechea, C.
KeywordsNeuropathic pain
Nociceptive pain
Cancer pain
Chronic pain
Issue Date2018
CitationBiochemical Pharmacology 157: 33-42 (2018)
AbstractThe discovery of the endocannabinoid system nearly three decades ago generated great interest among pain scientists. Moreover, its analogy with the opioid system in terms of evolutionary preservation, tissue localization and analgesic activity enabled a vast new field for the development of medicines addressed to those types of pain that still nowadays are difficult to manage. However, the main disadvantage that hampers the use of cannabinergic drugs as analgesics is their identification with recreational use, besides their psychotomimetic actions. Pain has traditionally been classified attending to the ailment duration (acute or chronic) and drugs are used according to the intensity of the pain to treat, but it is also important to target the mechanism involved despite the intensity or duration of pain. The present chapter reviews the study and use of cannabinoids attending separately to four classic types of pain: nociceptive, inflammatory, neuropathic and oncological, considering basic research (pain animal models) as well as clinical practice.
Publisher version (URL)http://dx.doi.org/10.1016/j.bcp.2018.07.033
Identifiersdoi: 10.1016/j.bcp.2018.07.033
issn: 0006-2952
e-issn: 1873-2968
Appears in Collections:(IQM) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.