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Título: | Antimicrobial and hemolytic studies of a series of polycations bearing quaternary ammonium moieties: Structural and topological effects |
Autor: | Mayr, Judith; Bachl, Jürgen CSIC; Schloßmann, Jens; Díaz Díaz, David CSIC ORCID | Palabras clave: | Topomers Antimicrobial polymers Hemolysis Ionenes Polycations Quaternary ammonium |
Fecha de publicación: | 1-feb-2017 | Editor: | Molecular Diversity Preservation International | Citación: | International Journal of Molecular Sciences 18 (2): 303 (2017) | Resumen: | A series of polycations bearing quaternary ammonium moieties have shown antimicrobial activity against the Gram-negative bacterium Escherichia coli. Different polymer topologies governed by a disubstituted aromatic core as well as different diamine-based linkers were found to influence the antimicrobial properties. Moreover, the hemolytic activity against human red blood cells was measured and demonstrated good biocompatibility and selectivity of these polycations for bacteria over mammalian cells. © 2017 by the authors; licensee MDPI, Basel, Switzerland. | Versión del editor: | https://doi.org/10.3390/ijms18020303 | URI: | http://hdl.handle.net/10261/177313 | DOI: | 10.3390/ijms18020303 |
Aparece en las colecciones: | (IQAC) Artículos |
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Antimicrobial and Hemolytic Studies of a Series.pdf | 1,24 MB | Adobe PDF | Visualizar/Abrir |
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