Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/175188
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Differential transcriptional profile through cell cycle progression in Arabidopsis cultures under simulated microgravity |
Autor: | Kamal, Khaled Y. CSIC ORCID CVN; van Loon, Jack JWA; Medina, F. Javier CSIC ORCID CVN ; Herranz, Raúl CSIC ORCID CVN | Palabras clave: | Plant Cell proliferation Cell growth Simulated microgravity Spaceflight Microarray |
Fecha de publicación: | 11-ene-2019 | Editor: | Elsevier | Citación: | Genomics S0888-7543(18)30536-6 (2019) | Resumen: | Plant cell proliferation is affected by microgravity during spaceflight, but involved molecular mechanisms, key for space agronomy goals, remain unclear. To investigate transcriptomic changes in cell cycle phases caused by simulated microgravity, an Arabidopsis immobilized synchronous suspension culture was incubated in a Random Positioning Machine. After simulation, a transcriptomic analysis was performed with two subpopulations of cells (G2/M and G1 phases enriched) and an asynchronous culture sample. Differential expression was found at cell proliferation, energy/redox and stress responses, plus unknown biological processes gene ontology groups. Overall expression inhibition was a common response to simulated microgravity, but differences peak at the G2/M phase and stress response components change dramatically from G2/M to the G1 subpopulation suggesting a differential adaptation response to simulated microgravity through the cell cycle. Cell cycle adaptation using both known stress mechanisms and unknown function genes may cope with reduced gravity as an evolutionary novel environment. | Descripción: | 31 p.-5 fig.-2 tab.-2 fig. supl. | Versión del editor: | https://doi.org/10.1016/j.ygeno.2019.01.007 | URI: | http://hdl.handle.net/10261/175188 | DOI: | 10.1016/j.ygeno.2019.01.007 | ISSN: | 0888-7543 | E-ISSN: | 1089-8646 |
Aparece en las colecciones: | (CIB) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
Kamal_Genomics_Submitted 2019.pdf | Postprint | 1,15 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
16
checked on 21-abr-2024
WEB OF SCIENCETM
Citations
15
checked on 27-feb-2024
Page view(s)
229
checked on 24-abr-2024
Download(s)
249
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.