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Title

Bioactive multi-elemental PEO-coatings on titanium for dental implant applications

AuthorsSantos-Coquillat, A.; Mohedano, M.; Martínez-Campos, Enrique; Arrabal, R.; Pardo, A.; Matykina, E.
KeywordsTitanium implant
Osteoblast
Osteoclast
Bioactive coating
Surface modification
Plasma electrolytic oxidation
Issue Date2019
PublisherElsevier
CitationMaterials Science and Engineering C-Materials for Biological Applications 97: 738- 752 (2019)
AbstractBioactive PEO (Plasma Electrolytic Oxidation) coatings were generated on Grade I commercially pure titanium for dentistry applications using a Ca/P-based electrolyte with added Si, Mg, Zn or F species. Surface characteristics, chemical composition and ion liberation of the coatings were characterized using SEM/EDS, X-ray diffraction, optical profilometry, contact angle and ICP-OES. Corrosion resistance (OCP and DC polarization) was evaluated in SBF. Osteoblastogenesis and osteoclastogenesis processes on PEO-coated Ti and non-coated Ti controls were assessed after 7 days and 5 days of cell culture, respectively. Monolayer formation and metabolic activity were evaluated for the MC3T3 preosteoblastic cell line. All PEO coatings favoured differentiation processes over proliferation and presented three times greater quantity of secreted collagen than non-coated Ti control. All coating enabled osteoclast differentiation, with differences in number and size of the osteoclasts between the materials.
Publisher version (URL)http://dx.doi.org/10.1016/j.msec.2018.12.097
URIhttp://hdl.handle.net/10261/174585
Identifiersdoi: 10.1016/j.msec.2018.12.097
issn: 1873-0191
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