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Título: | Spread of Pathogens in the Patient Transfer Network of US Hospitals |
Autor: | Fernández-Gracia, Juan CSIC ORCID ; Onnela, Jukka-Pekka; Barnett, Michael L.; Eguíluz, Víctor M. CSIC ORCID ; Christakis, Nicholas A. | Palabras clave: | Nosocomial Infection Medicare Patient Temporal Network Patient Transfer Network Neighbor |
Fecha de publicación: | 2017 | Editor: | Springer Nature | Citación: | Social, Cultural, and Behavioral Modeling. SBP-BRiMS 2017 (2017) | Resumen: | Antibiotic-resistant organisms, an increasing source of morbidity and mortality, have a natural reservoir in hospitals, and recent estimates suggest that almost 2 million people develop hospital-acquired infections each year in the US alone. We investigate the temporal network of transfers of Medicare patients across US hospitals over a 2-year period to learn about the possible role of hospital-to-hospital transfers of patients in the spread of infections. We analyze temporal, geographical, and topological properties of the transfer network and show that this network may serve as a substrate for the spread of infections. Finally, we study different strategies for the early detection of incipient epidemics on the temporal transfer network as a function of activation time of a subset of sensor hospitals. We find that using approximately 2% of hospitals as sensors, chosen based on their network in-degree, with an activation time of 7 days results in optimal performance for this early warning system, enabling the early detection of 80% of the C. difficile. cases with the hospitals in the sensor set activated for only a fraction of 40% of the time. | Descripción: | International Conference on Social Computing, Behavioral-Cultural Modeling and Prediction and Behavior Representation in Modeling and Simulation.-- Lee D., Lin YR., Osgood N., Thomson R. (eds). | Versión del editor: | https://doi.org/10.1007/978-3-319-60240-0_33 | URI: | http://hdl.handle.net/10261/174096 | DOI: | 10.1007/978-3-319-60240-0_33 | ISBN: | 978-3-319-60239-4 978-3-319-60240-0 (online) |
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