English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/173633
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

The effects of laser patterning 10CeTZP-Al2O3 nanocomposite disc surfaces: Osseous differentiation and cellular arrangement in vitro

AuthorsGoyos, Lidia ; Prado, Catuxa ; Díaz, Raquel; Fernández-García, Elisa ; Ismailov, Arnold; Kumpulainen, Tero; Levänen, Erkki; Torrecillas, Ramón
KeywordsCellular arrangement
Laser patterning
Osseous differentiation
Ceramic nanocomposite
Issue Date2018
CitationCeramics International 44(8): 9472-9478 (2018)
AbstractCustomized square grid arrangements of different groove depths (1.0, 1.5 and 3.0 µm) and separations (10 and 30 µm) were successfully laser patterned, using a nanosecond pulsed fibre laser, on the surface of 10 mol% ceria-stabilized zirconia and alumina (10CeTZP-AlO) nanocomposite discs (diameter: 10 mm; thickness: 1.5 mm). The patterned surfaces and the in vitro biological response of osteoblasts (SAOS-2) towards them were thoroughly analysed. In terms of composition, the laser treatment was found to cause superficial monoclinic-tetragonal zirconia phase transformation and alumina evaporation. In vitro, the most effective grid configuration for osseous differentiation was found to be 1.5 µm groove depth and 10 µm groove separation, and confocal microscopy revealed that the cells show a tendency to be sorted as groove depth increases. It is thought that custom-made patterns could be produced to guide cell attachment in vivo, which could favour implant integration and reduce healing time.
Identifiersdoi: 10.1016/j.ceramint.2018.02.164
issn: 0272-8842
e-issn: 1873-3956
Appears in Collections:(CINN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.