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In Situ Bone-Like Apatite Formation From a Bioeutectic SBF Dynamic Flow

AuthorsAza Moya, Antonio H. de ; Velásques, P.; Alemany, M. I.; Pena, Pilar ; Aza, Piedad N. de
Issue Date2007
PublisherJohn Wiley & Sons
CitationJ. Am. Ceram. Soc., 90 [4] 1200–1207 (2007)
AbstractIn a previous study, a new ceramic material (Bioeutectic s ), prepared by slow solidification through the eutectic temperaturecomposition region of the wollastonite–tricalcium phosphate system, was found to be bioactive in static-simulated body fluid. The eutectic material reacts by dissolving the pseudowollastonite phase and forming a hydroxyapatite-like porous structure by a pseudomorphic transformation of the tricalcium phosphate lamellae, which in turn mimics porous bone. Later, a hydroxyapatite- like layer is formed by precipitation on the surface of the material. In the present study, the bioactivity of the Bioeutectic s material was assessed in dynamic simulated body fluid in order to improve the ingrowth of new bone into implants (osteointegration). Samples of the material were soaked for 2 weeks in a dynamic simulated body fluid (1 mL/min) at 371C. The experiment showed that there is no precipitation of hydroxyapatitelike layer on the surface of a the material. Otherwise, a complete transformation of the eutectic material takes place, giving rise to a hydroxyapatite artificial porous bone. The dynamic model used in this study may be better than the usual static immersion model in imitating the physiological condition of bone-like apatite formation.
Publisher version (URL)DOI: 10.1111/j.1551-2916.2007.01534.x
Appears in Collections:(ICV) Artículos
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