English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/172557
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Does the mediterranean diet protect against stress-induced inflammatory activation in european adolescents? the HELENA study

AuthorsCarvalho, Kenia M. B.; Ronca, Débora B.; Michels, Nathalie; Huybrechts, Inge; Cuenca-Garcia, Magdalena; Marcos, Ascensión ; Molnar, Denes; Dallongeville, J.; Manios, Yannis; Schaan, Beatriz D.; Moreno, Luis A.; De Henauw, Stefaan; Carvalho, Livia A.
KeywordsDiet quality
Depressive symptoms
Risk factors
Epidemiology
Immune system
Prevention
Hypothalamic–pituitary–adrenal-HPA axis
Issue Date15-Nov-2018
PublisherMultidisciplinary Digital Publishing Institute
CitationNutrients 10(11): 1770 (2018)
AbstractStress increases inflammation but whether adherence to Mediterranean diet counteracts this association and how early can these effects be observed is not well known. We tested whether (1) cortisol is associated to inflammation, (2) cortisol is associated to the adolescent Mediterranean diet score (aMDS), (3) aMDS lessens inflammation, (4) aMDS associates with cortisol levels and inflammation. Two hundred and forty-two adolescents (137 females; 12.5–17.5 years old) provided salivary cortisol, blood and 2-day 24-h dietary recall from which aMDS was derived. Cortisol levels were associated with increased tumor necrosis factor (TNF-α B = 11.887, p = 0.001) when adjusted for age, gender, parental education and body mass index (BMI). Moreover, cortisol levels were inversely associated to adherence to the Mediterranean Diet (B = −1.023, p = 0.002). Adolescents with higher adherence to aMDS had lower levels of interleukins (IL) IL-1, IL-2, IL-6 and TNF-α, compared to those who did not adhere. The association between cortisol and TNF-α was no longer significant when aMDS was included in the model (B = 6.118, p = 0.139). In addition, comparing lower and higher aMDS groups, the association between cortisol and TNF-α was only observed in those with lower aMDS adherence. Our study suggests that adherence to the Mediterranean Diet may counteract the effect of stress on inflammatory biomarkers which may contribute to decreasing the risk of future mental health.
Publisher version (URL)http://dx.doi.org/10.3390/nu10111770
URIhttp://hdl.handle.net/10261/172557
DOI10.3390/nu10111770
E-ISSN2072-6643
Appears in Collections:(ICTAN) Artículos
Files in This Item:
File Description SizeFormat 
nutrients-10-01770.pdf485,97 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.