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Title

Cardiorespiratory fitness cutoff points for early detection of present and future cardiovascular risk in children: A 2-year follow-up study

AuthorsCastro-Piñero, José; Perez-Bey, Alejandro; Segura-Jiménez, Víctor; Aparicio, Virginia A.; Gómez Martínez, Sonia ; Izquierdo-Gómez, Rocío; Marcos, Ascensión ; Ruiz, Jonatan R.; Veiga, Óscar; Bandres, Fernando; Martínez Gómez, D. ; Carbonell-Baeza, Ana; Santiago, Catalina; Nova, Esther ; Díaz, L. E. ; Zapatera, Belén ; Veses, Ana M. ; Hernández, Aurora ; Gheorghe, Alina ; Mora-Vicente, Jesus; Gonzalez-Montesinos, Jose L.; Conde-Caveda, Julio; Ortega, F. B.; Padilla-Moledo, Carmen; Chillón, P.; Rosario Fernandez, Jorge del; Gonzalez Galo, Ana; Bellvis Guerra, Gonzalo; Delgado Alfonso, Alvaro; Parrilla, Fernando; Gomez, Roque; Gavala, Juan; Villagra, H. Ariel; Campo, Juan del; Cordente, Carlos; Díaz, Mario; Tejero-González, Carlos M.; Acha, Aitor; Moya, J. M.; Sanz, Alberto; Martínez Gómez, D. ; Cabanas-Sánchez, Verónica; Rodriguez-Romo, Gabriel; Garcia-Cervantes, Laura; Esteban-Cornejo, Irene; Lucia, Alejandro; Gómez-Gallego, Félix
Issue Date2017
PublisherElsevier
CitationMayo Clinic Proceedings 92(12): 1753-1762 (2017)
Abstract[Objective]: To examine the association between cardiorespiratory fitness (CRF) at baseline and cardiovascular disease (CVD) risk in 6- to 10-year-olds (cross-sectional) and 2 years later (8- to 12-year-olds [longitudinal]) and whether changes with age in CRF are associated with CVD risk in children aged 8 to 12 years. [Patients and Methods]: Spanish primary schoolchildren (n=236) aged 6 to 10 years participated at baseline. Of the 23 participating primary schools, 22% (n=5) were private schools and 78% (n=18) were public schools. The dropout rate at 2-year follow-up was 9.7% (n=23). The 20-m shuttle run test was used to estimate CRF. The CVD risk score was computed as the mean of 5 CVD risk factor standardized scores: sum of 2 skinfolds, systolic blood pressure, insulin/glucose, triglycerides, and total cholesterol/high-density lipoprotein cholesterol. [Results]: At baseline, CRF was inversely associated with single CVD risk factors (all P<.05) and CVD risk score at baseline and follow-up (P<.001). Cardiorespiratory fitness cutoff points of 39.0 mL/kg per minute or greater in boys and 37.5 mL/kg per minute or greater in girls are discriminative to identify CVD risk in childhood (area under the curve, >0.85; P<.001) and to predict CVD risk 2 years later (P=.004). Persistent low CRF or the decline of CRF from 6-10 to 8-12 years of age is associated with increased CVD risk at age 8 to 12 years (P<.001). [Conclusion]: During childhood, CRF is a strong predictor of CVD risk and should be monitored to identify children with potential CVD risk.
DescriptionOn behalf of the UP&DOWN Study Group.
URIhttp://hdl.handle.net/10261/171275
Identifiersdoi: 10.1016/j.mayocp.2017.09.003
e-issn: 1942-5546
issn: 0025-6196
Appears in Collections:(ICTAN) Artículos
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