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dc.contributor.authorRodríguez-Concepción, Manuel-
dc.contributor.authorAvalos, Javier-
dc.contributor.authorBonet, M. Luisa-
dc.contributor.authorBoronat, Albert-
dc.contributor.authorGomez-Gomez, Lourdes-
dc.contributor.authorHornero-Méndez, Dámaso-
dc.contributor.authorLimón, M. Carmen-
dc.contributor.authorMeléndez-Martínez, Antonio J.-
dc.contributor.authorOlmedilla Alonso, Begoña-
dc.contributor.authorPalou, Andreu-
dc.contributor.authorRibot, Joan-
dc.contributor.authorRodrigo, María Jesús-
dc.contributor.authorZacarías, Lorenzo-
dc.contributor.authorZhu, Changfu-
dc.date.accessioned2018-10-09T11:36:27Z-
dc.date.available2018-10-09T11:36:27Z-
dc.date.issued2018-
dc.identifierdoi: 10.1016/j.plipres.2018.04.004-
dc.identifiere-issn: 1873-2194-
dc.identifierissn: 0163-7827-
dc.identifier.citationProgress in Lipid Research 70: 62-93 (2018)-
dc.identifier.urihttp://hdl.handle.net/10261/170827-
dc.description.abstractCarotenoids are lipophilic isoprenoid compounds synthesized by all photosynthetic organisms and some non-photosynthetic prokaryotes and fungi. With some notable exceptions, animals (including humans) do not produce carotenoids de novo but take them in their diets. In photosynthetic systems carotenoids are essential for photoprotection against excess light and contribute to light harvesting, but perhaps they are best known for their properties as natural pigments in the yellow to red range. Carotenoids can be associated to fatty acids, sugars, proteins, or other compounds that can change their physical and chemical properties and influence their biological roles. Furthermore, oxidative cleavage of carotenoids produces smaller molecules such as apocarotenoids, some of which are important pigments and volatile (aroma) compounds. Enzymatic breakage of carotenoids can also produce biologically active molecules in both plants (hormones, retrograde signals) and animals (retinoids). Both carotenoids and their enzymatic cleavage products are associated with other processes positively impacting human health. Carotenoids are widely used in the industry as food ingredients, feed additives, and supplements. This review, contributed by scientists of complementary disciplines related to carotenoid research, covers recent advances and provides a perspective on future directions on the subjects of carotenoid metabolism, biotechnology, and nutritional and health benefits.-
dc.description.sponsorshipAuthors belong to the Spanish Carotenoid Network (CaRed) funded by the Spanish MINECO (Ministry of Economy, Industry and Competitiveness) grant BIO2015-71703-REDT, the European Carotenoid Network (EuroCaroten) funded by the European Commission COST ActionCA15136, and the Ibero-American Carotenoid Network (IberCarot) funded by the Ibero-American Programme for Science, Technology and Development (CYTED) grant 112RT0445. Research on carotenoids at the authors' individual laboratories was supported by Spanish MINECO grants BIO2014-59092-P to MRC, BIO2015-69613-R to JA and MCL, AGL2013-43522-R to AB, BIO2016-77000-R to LGG, AGL2014-53195-R to DHM, AGL2015-67019-P to AP, BIO2014-54441-P to CZ, and AGL2015-70218 to LZ and MJR; Instituto de Salud Carlos III-FEDER grant PI16/01991 to BOA; Generalitat de Catalunya grants 214SGR-1434 to MRC and AB and 2014SGR-1296 to CZ; and Junta de Andalucia grants P10-CTS-6638 to JA and P12-AGR-1287 to AJMM. We also acknowledge the financial support of the CERCA Programme of the Generalitat de Catalunya and the Severo Ochoa Programme for Centres of Excellence in R&D 2016–2019 to CRAG (SEV-2015-0533).-
dc.publisherElsevier-
dc.relationMINECO/ICTI2013-2016/BIO2015-71703-REDT-
dc.relationMINECO/ICTI2013-2016/AGL2015-67019-P-
dc.relationMINECO/ICTI2013-2016/AGL2014-53195-R-
dc.relationMINECO/ICTI2013-2016/BIO2016-77000-R-
dc.relationMINECO/ICTI2013-2016/AGL2013-43522-R-
dc.relationMINECO/ICTI2013-2016/BIO2015-69613-R-
dc.relationMINECO/ICTI2013-2016/BIO2014-59092-P-
dc.relationMINECO/ICTI2013-2016/BIO2014-54441-P-
dc.relationMINECO/ICTI2013-2016/AGL2015-70218-R-
dc.relationMINECO/ICTI2013-2016/SEV-2015-0533-
dc.relation.isversionofPostprint-
dc.rightsopenAccessen_EN
dc.subjectCarotenoid-
dc.subjectHealth-
dc.subjectMetabolism-
dc.subjectNutrition-
dc.subjectPigment-
dc.subjectBiotechnology-
dc.titleA global perspective on carotenoids: Metabolism, biotechnology, and benefits for nutrition and health-
dc.typeartículo-
dc.relation.publisherversionhttps://doi.org/10.1016/j.plipres.2018.04.004-
dc.date.updated2018-10-09T11:36:28Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.contributor.funderJunta de Andalucía-
dc.contributor.funderGeneralitat de Catalunya-
dc.contributor.funderInstituto de Salud Carlos III-
dc.contributor.funderMinisterio de Economía y Competitividad (España)-
dc.contributor.funderEuropean Commission-
dc.contributor.funderMinisterio de Economía, Industria y Competitividad (España)-
dc.relation.csic-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003329es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004587es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100002809es_ES
dc.identifier.pmid29679619-
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