English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/169989
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Diet: Cause or Consequence of the Microbial Profile of Cholelithiasis Disease?

AuthorsGutiérrez-Díaz, Isabel; Molinero, Natalia; Cabrera, Ana; Rodríguez García, José Ignacio; Margolles Barros, Abelardo ; Delgado, Susana ; González, Sonia
KeywordsDiet
Polyphenols
Fiber
Cholelithiasis
Biliary microbiota
Issue Date14-Sep-2018
PublisherMultidisciplinary Digital Publishing Institute
CitationNutrients 10(9): 1307 (2018)
AbstractRecent dietary habits and lifestyle could explain the shaping of the gut microbiota composition and, in consequence, the increasing prevalence of certain pathologies. However, little attention has been paid to the influence of diet on microbiotas, other than the gut microbiota. This is important in cholelithiasis, given that changes in the production of bile acids may affect gallbladder microbial communities. Our aim was to assess the association between regular dietary intake and gallbladder microbial composition. Fourteen adults with cholelithiasis and 14 controls, sex-age-matched and without gastrointestinal pathology, were included. Diet was assessed through a food frequency questionnaire and quantification of gallbladder microbiota sequences by Illumina 16S rRNA gene-based analysis. The cholelithiasic patients showed greater intake of potatoes and lower consumption of vegetables, non-alcoholic drinks, and sauces, which resulted in a lower intake of energy, lipids, digestible polysaccharides, folate, calcium, magnesium, vitamin C, and some phenolic compounds. Regarding the altered bile microorganisms in cholelithiasic patients, dairy product intake was negatively associated with the proportions of Bacteroidaceae and Bacteroides, and several types of fiber, phenolics, and fatty acids were linked to the abundance of Bacteroidaceae, Chitinophagaceae, Propionibacteraceae, Bacteroides, and Escherichia-Shigella. These results support a link between diet, biliary microbiota, and cholelithiasis.
Publisher version (URL)https://doi.org/10.3390/nu10091307
URIhttp://hdl.handle.net/10261/169989
DOI10.3390/nu10091307
ISSN2072-6643
Appears in Collections:(IPLA) Artículos
Files in This Item:
File Description SizeFormat 
nutrients-10-01307-v2.pdf1,85 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.