English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/165152
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

A role for the host in the roadmap to diabetes stem cell therapy

AuthorsSoria Escoms, Bernat ; Montanya, Eduard; Martín, Franz ; Hmadcha, Abdelkrim
Issue Date2016
PublisherAmerican Diabetes Association
CitationDiabetes 65(5): 1155-1157 (2016)
AbstractStem cells represent an unlimited source for cell therapy, and considerable efforts have been made to overcome barriers to introducing this revolutionary therapy into clinical practice. Briefly, the following actions must be taken: 1) design in vitro differentiation strategies to generate either mature postmitotic b-cells or b-cell progenitors that may be safely implanted into the host (e.g., without uncontrolled proliferation), 2) devise selection methods to produce a pure b-cell population, 3) validate standard characterization protocols to determine the real differentiation stage of the cells ready to be transplanted, 4) obtain encapsulation devices to implant the cells, 5) develop preclinical controls in representative animal models, and 6) define cell-host interactions.
URIhttp://hdl.handle.net/10261/165152
Identifiersdoi: 10.2337/dbi16-0003
e-issn: 1939-327X
issn: 0012-1797
Appears in Collections:(CABIMER) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.