Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/162498
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Título: | Multilevel selection of bcrABDR- mediated bacitracin resistance in Enterococcus faecalis from chicken farms |
Autor: | Chen, Mu-Ya; Lira, Felipe; Liang, Hua-Qing; Wu, Rui-Ting; Duan, Jia-Hong; Liao, Xiao-Ping; Martínez, José L. CSIC ORCID; Liu, Ya-Hong; Sun, Jian | Fecha de publicación: | 2016 | Citación: | Scientific Reports | Resumen: | In this study we isolated 109 Enterococcus faecalis from chicken faecal samples in 6 provinces of China to investigate the prevalence and transmission mechanism of the bacitracin resistance locus bcrABDR in E. faecalis. Thirty-seven bcrABDR-positive E. faecalis were detected with 26 di erent PFGE clusters. The MLST of 14 positive strains belonged to ST16 and we also detected three new sequence types. S1-PFGE analysis indicated that the locus was located on plasmids presenting di erent sizes, with the most prevalent size being ~50 kb (13/37). Sequence analysis revealed that 17 out of the 37 strains harbored a 5400-bp central region, in which locus bcrABDR was bracketed by two ISEnfa1 of the same orientation. Two types of bcrABDR alleles, di ering in around 10% of their sequence were found. In silico analysis showed that bcrABDR is present in a variety of bacteria including the chicken commensal Enterococcus cecorum. Our results indicate that the use of bacitracin at farms might trigger the emergence and spread of the bacitracin resistance determinant bcrABDR among human bacterial pathogens. The finding of bcrABDR in the chicken commensal E. cecorum indicates that farm animals microbiota can be an important reservoir of resistance genes with relevance for human health. | Versión del editor: | https://www.nature.com/articles/srep34895.pdf | URI: | http://hdl.handle.net/10261/162498 | DOI: | 10.1038/srep34895 |
Aparece en las colecciones: | (CNB) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
srep34895.pdf | Articulo | 696,78 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
PubMed Central
Citations
10
checked on 10-abr-2024
SCOPUSTM
Citations
20
checked on 17-abr-2024
WEB OF SCIENCETM
Citations
17
checked on 25-feb-2024
Page view(s)
222
checked on 24-abr-2024
Download(s)
207
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
Artículos relacionados:
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.