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dc.contributor.authorComas, Iñakies_ES
dc.date.accessioned2018-01-23T12:15:04Z-
dc.date.available2018-01-23T12:15:04Z-
dc.date.issued2017-
dc.identifier.citationStrain Variation in the Mycobacterium tuberculosis Complex: Its Role in Biology, Epidemiology and Control 4: 79-93 (2017)es_ES
dc.identifier.isbn978-3-319-64371-7-
dc.identifier.issn0065-2598-
dc.identifier.urihttp://hdl.handle.net/10261/159480-
dc.descriptionGagneux, S. (ed) .-- 16 páginases_ES
dc.description.abstractThe application of next generation sequencing technologies has opened the door to a new molecular epidemiology of tuberculosis, in which we can now look at transmission at a resolution not possible before. At the same time, new technical and analytical challenges have appeared, and we are still exploring the wider potential of this new technology. Whole genome sequencing in tuberculosis still requires bacterial cultures. Thus, although whole genome sequencing has revolutionized the interpretation of transmission patterns, it is not yet ready to be applied at the point-of-care. In this chapter, I will review the promises and challenges of genomic epidemiology, as well as some of the new questions that have arisen from the use of this new technology. In addition, I will examine the role of molecular epidemiology within the general frame of global tuberculosis control and how genomic epidemiology can contribute towards the elimination of the disease.es_ES
dc.description.sponsorshipWork in my laboratory is supported by the Spanish National Foundation (MINECO SAF2013-43521-R) and the European Research Council (638553-TB-ACCELERATE).es_ES
dc.language.isoenges_ES
dc.publisherSpringer Naturees_ES
dc.relationMINECO/ICTI2013-2016/SAF2013-43521-Res_ES
dc.relationinfo:eu-repo/grantAgreement/EC/H2020/638553es_ES
dc.relation.ispartofseriesAdvances in Experimental Medicine and Biologyes_ES
dc.relation.ispartofseries1019-
dc.relation.isversionofPostprintes_ES
dc.rightsopenAccesses_ES
dc.subjectTransmissiones_ES
dc.subjectGenome sequencinges_ES
dc.subjectOutbreakes_ES
dc.subjectMutation ratees_ES
dc.titleGenomic Epidemiology of Tuberculosises_ES
dc.typecapítulo de libroes_ES
dc.identifier.doi10.1007/978-3-319-64371-7_4-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/ 10.1007/978-3-319-64371-7_4es_ES
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
dc.contributor.funderEuropean Research Counciles_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003329es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000781es_ES
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