English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/157725
logo share SHARE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Secondary metabolites from two species of Tolpis and their biological activities

AuthorsTriana, Jorge ; López, Mariana; Pérez, Francisco Javier; Rico, Milagros; López, Aroa; Estévez, Francisco; Marrero, María Teresa; Brouard, Ignacio ; León, Francisco
Tolpis proustii
Tolpis lagopoda
Issue Date1-Nov-2012
PublisherMultidisciplinary Digital Publishing Institute
CitationMolecules 17(11): 12895-12909 (2012)
AbstractPhytochemical research of two Tolpis species, T. proustii and T. lagopoda, led to the isolation of three new compounds: 30-chloro-3β-acetoxy-22α-hydroxyl-20(21)- taraxastene (1), 3β,22α-diacetoxy-30-ethoxy-20(21)-taraxastene (2) and 3β,28-dihydroxy11α-hydroperoxy-12-ursene (3). The structures of the new compounds were elucidated by means of extensive IR, NMR, and MS data and by comparison of data reported in the literature. The in vitro antioxidant activities of the extracts were assessed by the DPPH and ABTS scavenging methods. The cytotoxicity of several known compounds and its derivatives was also assessed against human myeloid leukemia K-562 and K-562/ADR cell lines.
Appears in Collections:(IPNA) Artículos
Files in This Item:
File Description SizeFormat 
molecules-17-12895.pdf248,51 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.