English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/154081
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Synaptic regulation of the astrocyte calcium signal

AuthorsPerea, Gertrudis ; Araque, Alfonso
KeywordsAstrocyte-neuron Signaling intracellular calcium Calcium waves Synaptic activity
Issue Date2005
PublisherSpringer
CitationJOURNAL OF NEURAL TRANSMISSION 112: 127- 135 (2005)
AbstractDuring the last years, a great amount of evidence demonstrates the existence of bidirectional communication between astrocytes and neurons, which has revealed an important active role of astrocytes in the physiology of the nervous system. As a consequence of this evidence, a new concept of the synaptic physiology ->the tripartite synapse>- has been proposed, in which the synapse is formed by three functional elements, i.e., the pre- and post-synaptic elements and the surrounding astrocytes. In this scenario astrocytes play an active role as dynamic regulatory elements in neurotransmission by reciprocally exchanging information with the pre- and postsynaptic elements. The control of the Ca2+ excitability in astrocytes is a key element in this loop of information exchange. In the present article we review and discuss our current knowledge of the properties of the astrocyte intracellular Ca2+ signal and its modulation by the synaptic activity. © Springer-Verlag 2004.
URIhttp://hdl.handle.net/10261/154081
DOI10.1007/s00702-004-0170-7
Identifiersdoi: 10.1007/s00702-004-0170-7
issn: 0300-9564
Appears in Collections:(IC) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.