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dc.contributor.authorGonzález Jiménez, Emilioes_ES
dc.contributor.authorSchmidt-RioValle, Jacquelinees_ES
dc.contributor.authorSinausia-Nieva, Lauraes_ES
dc.contributor.authorPerona, Javier S.es_ES
dc.date.accessioned2017-06-21T11:11:58Z-
dc.date.available2017-06-21T11:11:58Z-
dc.date.issued2017-04-21-
dc.identifier.citationBiological Research For Nursing 19 (4): 419-427 (2017)es_ES
dc.identifier.issn1099-8004-
dc.identifier.urihttp://hdl.handle.net/10261/151788-
dc.description28 Páginas; 2 Ilustraciones; 4 tablas más 1 suplementariaes_ES
dc.description.abstractBackground: Breastfeeding duration has been associated with less low-grade inflammation in healthy adolescents, but there is scarce information regarding obese subjects. This study aimed to evaluate whether exclusive breastfeeding is related to serum concentrations of inflammatory markers in a population of Spanish adolescents. Method: A cross-sectional study was performed on 1,001 adolescents (13.2 ± 1.2 years) randomly recruited from schools in southeast Spain. Data on breastfeeding duration were collected via a parental questionnaire. Interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) were determined by enzyme-linked immunosorbent assay. C-reactive protein (CRP) was determined by solid-phase chemiluminescent immunometric assay. Results: Nonadjusted and adjusted multivariate correlation analyses confirmed a strong association (p < .001, 95% confidence interval) between the three markers of inflammation and exclusive breastfeeding duration. No significant differences were observed for IL-6, TNF-α, and CRP serum concentrations among normal weight, overweight, and obese adolescents, except for IL-6 between normal weight and obese subjects. Likewise, no significant association was found between these markers of inflammation and body mass index (BMI) z-score. Conclusions: We found a possible association between inflammatory markers and exclusive breastfeeding duration in adolescents, regardless of their BMI. This finding suggests that increased body weight or obesity might not mediate the association between breastfeeding and inflammation. These results contribute to the understanding of the relationship between breastfeeding and inflammatory markers in adolescents.es_ES
dc.description.sponsorshipThis work was supported by funds from Comisión Interministerial de Ciencia y Tecnología (CYCIT, AGL2011-23810). Laura Sinausía was the recipient of a grant from the Spanish Program for Research Personnel Training (Ministry of Economy and Competitiveness).es_ES
dc.language.isoenges_ES
dc.publisherSage Publicationses_ES
dc.relation.isversionofPostprintes_ES
dc.rightsopenAccesses_ES
dc.subjectAdolescentses_ES
dc.subjectBreastfeedinges_ES
dc.subjectInflammationes_ES
dc.subjectObesityes_ES
dc.titleAssociation of Exclusive Breastfeeding Duration With Systemic Inflammation Markers in Adolescents: A Cross-Sectional Studyes_ES
dc.typeArtículoes_ES
dc.identifier.doi10.1177/1099800417705464-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1177/1099800417705464es_ES
dc.identifier.e-issn1552-4175-
dc.embargo.terms2018-04-21es_ES
dc.contributor.funderComisión Interministerial de Ciencia y Tecnología, CICYT (España)es_ES
dc.contributor.funderMinisterio de Economía y Competitividad (España)es_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.identifier.funderhttp://dx.doi.org/10.13039/501100007273es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003329es_ES
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