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Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/14827

Spectroscopic techniques applied to the study of laminin fragments inserted into model membranes

AutorCrosas, E.; Egea, M. A.; Reig Isart, Francesca
Palabras claveLaminin
Fecha de publicación1-mar-2006
CitaciónJournal of Colloid and Interface Science 295(1): 264-269 (2006)
ResumenThe influence of four laminin-derived peptides on bilayer organization is studied. Spectroscopic methods applied were based on pyrene fluorescence properties (quenching, I1/I3, and monomer/excimer equilibrium), asymmetric membrane fluorescence (NBD-PE/dithionite), and polarization fluorescence (TMA-DPH). Also, the ability of these peptides to release carboxyfluorescein entrapped in vesicles was determined. Results suggest that these peptides do not noticeably modify the packing and motion of lipids (in the gel state), but coat its surface, preventing penetration of quenchers and chemical reactants. Nevertheless, their presence promotes a soft release of entrapped CF after incubation at 37 °C.
Descripción6 pages, 6 figures.-- PMID: 16162352 [PubMed].-- Available online Sep 12, 2005.
Versión del editorhttp://dx.doi.org/10.1016/j.jcis.2005.07.064
ISSN0021-9797 (Print)
1095-7103 (Online)
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