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Título

1,135 Genomes Reveal the Global Pattern of Polymorphism in Arabidopsis thaliana

Autor Alonso-Blanco, Carlos; Andrade, J.; Becker, C.; Bemm, F.; Bergelson, J; Borgwardt, KM; Cao, J; Chae, E; Dezwaan, TM; Ding, W; Ecker, JR; Exposito-Alonso, M; Farlow, A; Fitz, J; Gan, XC; Grimm, DG; Hancock, AM; Henz, SR; Holm, S; Horton, M; Jarsulic, M; Kerstetter, RA; Korte, A; Korte, P; Lanz, C; Lee, CR; Meng, DZ; Michael, TP; Mott, R; Muliyati, NW; Nagele, T; Nagler, M; Nizhynska, V; Nordborg, M; Novikova, PY.; Picó, F. Xavier ; Platzer, A; Rabanal, FA; Rodriguez, A; Rowan, BA; Salome, PA; Schmid, KJ; Schmitz, RJ; Seren, U; Sperone, FG; Sudkamp, M; Svardal, H; Tanzer, MM; Todd, D; Volchenboum, SL; Wang, CM; Wang, G; Wang, X; Weckwerth, W; Weigel, D; Zhou, XF
Palabras clave Population expansion
GWAS
Glacial refugia
1001 Genomes
Arabidopsis thaliana
Fecha de publicación 2016
EditorCell Press
Citación Cell 166: 481- 491 (2016)
ResumenArabidopsis thaliana serves as a model organism for the study of fundamental physiological, cellular, and molecular processes. It has also greatly advanced our understanding of intraspecific genome variation. We present a detailed map of variation in 1,135 high-quality re-sequenced natural inbred lines representing the native Eurasian and North African range and recently colonized North America. We identify relict populations that continue to inhabit ancestral habitats, primarily in the Iberian Peninsula. They have mixed with a lineage that has spread to northern latitudes from an unknown glacial refugium and is now found in a much broader spectrum of habitats. Insights into the history of the species and the fine-scale distribution of genetic diversity provide the basis for full exploitation of A. thaliana natural variation through integration of genomes and epigenomes with molecular and non-molecular phenotypes.
URI http://hdl.handle.net/10261/145996
Identificadoresdoi: 10.1016/j.cell.2016.05.063
issn: 0092-8674
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