Family size in primary trisonic analysis

Abstract

[EN] In the planning of any genetic experiment the minimum family size should be determined in order to minimize the total efforts, while fulfilling the objectives of the experiment. In the present study, the family size has been determined for different methods and extra chromosome transmission rates in primary trisomic analysis. The statistical criterion used was the "minimax" solution. Tables for both F2 and backcross generation for different transmission rates and type of trisomic inheritance were developed.

[ES] En el diseño de cualquier experimento genético, se debe determinar el tamaño mínimo de las familias que permita, minimizando el esfuerzo total, alcanzar los objetivos previstos. Utilizando el criterio estadístico "minimax" se han calculado los tamaños de familia mínimos en la localización de genes mediante trisómicos primarios.