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Mastitis modifies the biogenic amines profile in human milk, with significant changes in the presence of histamine, putrescine and spermine

AuthorsPérez, Marta M.; Ladero Losada, Víctor Manuel ; Redruello, Begoña ; Fernández, Leonides; Río Lagar, Beatriz del ; Rodríguez Gómez, Juan M.; Martín, M. Cruz ; Fernández García, María ; Álvarez González, Miguel Ángel
Issue Date1-Sep-2016
PublisherPublic Library of Science
CitationPLoS ONE 11(9): e0162426 (2016)
AbstractBiogenic amines (BAs) are low molecular weight nitrogenous organic compounds with different biological activities. Putrescine, spermidine and spermine are essential for the development of the gut and immune system of newborns, and are all found in human milk. Little is known, however, about the role of histamine, tyramine or cadaverine in breast milk. Nor is it known whether mastitis alters the BA composition of milk. The BA profile of human milk, and the influence of mastitis on BA concentrations, were therefore investigated. Putrescine, spermidine and spermine were the main BAs detected. In mastitis-affected milk, the concentrations of putrescine, spermine and histamine were higher.
Publisher version (URL)https://doi.org/10.1371/journal.pone.0162426
Identifiersissn: 1932-6203
Appears in Collections:(IPLA) Artículos
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