English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/139967
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Título

Is Hybridization a Source of Adaptive Venom Variation in Rattlesnakes? A Test, Using a Crotalus scutulatus × viridis Hybrid Zone in Southwestern New Mexico

AutorZancolli, Giulia; Bake, Timothy G.; Barlow, Axel; Bradley, Rebecca K.; Calvete, Juan J. ; Carter, Kimberley C.; Jager, Kaylah de; Owens, John Benjamin; Price, Jenny Forrester; Sanz, Libia ; Scholes-Higham, Amy; Shier, Liam; Wood, Liam; Wüster, Catharine E.; Wüster, Wolfgang
Palabras claveAdaptation
Crotalus
Evolution
Hybridization
Introgression
Mojave toxin
Molecular evolution
Venom
Fecha de publicación16-jun-2016
EditorMolecular Diversity Preservation International
CitaciónToxins 8(6): E188 (2016)
ResumenVenomous snakes often display extensive variation in venom composition both between and within species. However, the mechanisms underlying the distribution of different toxins and venom types among populations and taxa remain insufficiently known. Rattlesnakes (Crotalus, Sistrurus) display extreme inter- and intraspecific variation in venom composition, centered particularly on the presence or absence of presynaptically neurotoxic phospholipases A₂ such as Mojave toxin (MTX). Interspecific hybridization has been invoked as a mechanism to explain the distribution of these toxins across rattlesnakes, with the implicit assumption that they are adaptively advantageous. Here, we test the potential of adaptive hybridization as a mechanism for venom evolution by assessing the distribution of genes encoding the acidic and basic subunits of Mojave toxin across a hybrid zone between MTX-positive Crotalus scutulatus and MTX-negative C. viridis in southwestern New Mexico, USA. Analyses of morphology, mitochondrial and single copy-nuclear genes document extensive admixture within a narrow hybrid zone. The genes encoding the two MTX subunits are strictly linked, and found in most hybrids and backcrossed individuals, but not in C. viridis away from the hybrid zone. Presence of the genes is invariably associated with presence of the corresponding toxin in the venom. We conclude that introgression of highly lethal neurotoxins through hybridization is not necessarily favored by natural selection in rattlesnakes, and that even extensive hybridization may not lead to introgression of these genes into another species.
DescripciónArtículo electrónico, 16 páginas, 5 figuras, 4 tablas (2 en material suplementario).
Versión del editorhttp://dx.doi.org/10.3390/toxins8060188
URIhttp://hdl.handle.net/10261/139967
DOI10.3390/toxins8060188
E-ISSN2072-6651
Aparece en las colecciones: (IBV) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
2016 Toxins 008-00188.pdf1,86 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.