English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/136587
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

High-speed multi-exposure laser speckle contrast imaging with a single-photon counting camera

AuthorsDragojević, Tanja; Bronzi, Danilo; Varma, Hari M.; Valdés, Claudia P.; Castellví, Clara; Villa, Federica A.; Tosi, Alberto; Justicia, Carles ; Zappa, Franco; Durduran, Turgut
KeywordsAvalanche photodiodes (APDs)
Spectroscopy, speckle
Photon counting
Speckle imaging
Issue Date14-Jul-2015
PublisherOptical Society of America
CitationBiomedical Optics Express 6(8): 2865-2876 (2015)
AbstractLaser speckle contrast imaging (LSCI) has emerged as a valuable tool for cerebral blood flow (CBF) imaging. We present a multiexposure laser speckle imaging (MESI) method which uses a high-frame rate acquisition with a negligible inter-frame dead time to mimic multiple exposures in a single-shot acquisition series. Our approach takes advantage of the noise-free readout and high-sensitivity of a complementary metaloxide- semiconductor (CMOS) single-photon avalanche diode (SPAD) array to provide real-time speckle contrast measurement with high temporal resolution and accuracy. To demonstrate its feasibility, we provide comparisons between in vivo measurements with both the standard and the new approach performed on a mouse brain, in identical conditions.
Publisher version (URL)http://dx.doi.org/10.1364/BOE.6.002865
URIhttp://hdl.handle.net/10261/136587
DOI10.1364/BOE.6.002865
Identifiersdoi: 10.1364/BOE.6.002865
issn: 2156-7085
Appears in Collections:(IIBB) Artículos
Files in This Item:
File Description SizeFormat 
Dragojevic-BiomOptExpress-2015-v6-p2865.pdf1,42 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.