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| Título: | CD53 |
Autor: | Lazo, Pedro A. CSIC ORCID ; Barcia, R. | Palabras clave: | Ox-44 OX44 MOX44 Tspan25l Cell surface glycoprotein CD53 CD53 antigen Tetraspanin-25 Tspan-25 Leukocyte surface antigen CD53 |
Fecha de publicación: | 2012 | Editor: | Springer Nature | Citación: | Encyclopedia of Signalling Molecules: 343-347 (2012) | Resumen: | CD53 is one of the least characterized members of the tetraspanin family. CD53 is integrated in the tetraspanin web, and sends intracellular signals, directly or indirectly via PKC, AKT, and γ-glutamyl transpeptidase (GGT). Its expression can affect cell survival, resistance to apoptosis, and radiation sensitivity. In B-cell development CD53 is a marker of mature B cells. In human B-cell malignancies, the pattern of tetraspanin expression identifies the developmental stage of the corresponding tumors. The pattern of tetraspanins can be used to differentiate B-cell malignancies in an individual patient with several lymphoid tumors. | URI: | http://hdl.handle.net/10261/136021 | DOI: | 10.1007/978-1-4419-0461-4_566 | Identificadores: | doi: 10.1007/978-1-4419-0461-4_566 isbn: 978-1-4419-0460-7 |
| Aparece en las colecciones: | (IBMCC) Libros y partes de libros |
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| accesoRestringido.pdf | 15,38 kB | Adobe PDF |  Visualizar/Abrir |
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