English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/135620
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Title

Functional Gene Networks: R/Bioc package to generate and analyse gene networks derived from functional enrichment and clustering

AuthorsAibar, Sara ; Fontanillo, Celia ; Droste, Conrad ; De Las Rivas, Javier
Issue Date2015
PublisherOxford University Press
CitationBioinformatics 31(10): 1686-1688 (2015)
AbstractFunctional Gene Networks (FGNet) is an R/Bioconductor package that generates gene networks derived from the results of functional enrichment analysis (FEA) and annotation clustering. The sets of genes enriched with specific biological terms (obtained from a FEA platform) are transformed into a network by establishing links between genes based on common functional annotations and common clusters. The network provides a new view of FEA results revealing gene modules with similar functions and genes that are related to multiple functions. In addition to building the functional network, FGNet analyses the similarity between the groups of genes and provides a distance heatmap and a bipartite network of functionally overlapping genes. The application includes an interface to directly perform FEA queries using different external tools: DAVID, GeneTerm Linker, TopGO or GAGE; and a graphical interface to facilitate the use.
DescriptionThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License.
Publisher version (URL)http://dx.doi.org/10.1093/bioinformatics/btu864
URIhttp://hdl.handle.net/10261/135620
DOI10.1093/bioinformatics/btu864
Identifiersdoi: 10.1093/bioinformatics/btu864
e-issn: 1460-2059
issn: 1367-4803
Appears in Collections:(IBMCC) Artículos
Files in This Item:
File Description SizeFormat 
Bioc package.pdf292,84 kBAdobe PDFThumbnail
View/Open
Show full item record
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.