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Effect of the consumption of Lactobacillus coryniformis CECT5711 strain on the immune response of healthy adults

AuthorsRedondo, Noemí ; Mujico, Jorge R. ; Díaz, L. E. ; Hernández, Aurora ; Gheorghe, Alina ; Bermejo, M.; Díaz-Ropero, M. Paz; Olivares, Marta ; Nova, Esther ; Marcos, Ascensión
Issue Date2014
PublisherSociedad Española de Probióticos y Prebióticos
CitationV Workshop Probióticos Prebióticos y Salud: Evidencia científica 2014, Valencia 23-24 Enero
AbstractAmong the various health-promoting functions of probiotics, much attention has been paid to their immunological function, although the immune response to probiotics is generally regarded to be strain dependent. For this purpose, the main objective of this study was to assess the effect of Lactobacillus coryniformis CECT5711 on the immune response of healthy adults during 6 weeks of treatment in a Hepatitis A vaccine model. One hundred twenty three volunteers were randomized into a placebo group, a probiotic group or a mixed group. Blood samples were taken at the beginning, after two weeks of treatment just before the vaccination and at the end of the study. Phagocytic and Natural Killer activities were measured in blood samples, besides the levels of cytokines using Luminex technology, leukocyte subsets assessed by monoclonal antibodies and specific Hepatitis A antibodies with a competitive ELISA.
Appears in Collections:(ICTAN) Comunicaciones congresos
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