English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/132624
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Acetylides from alkyl propiolates as building blocks for C3 homologation

AuthorsTejedor, David ; López-Tosco, Sara ; Cruz-Acosta, Fabio ; Méndez-Abt, Gabriela ; García-Tellado, Fernando
Issue Date9-Mar-2009
PublisherJohn Wiley & Sons
CitationAngewandte Chemie - International Edition 48: 2090-2098 (2009)
AbstractAlkyl propiolates are reagents with a versatile reactivity profile that entirely remains in the C3-homologated product for further elaboration. To be effective, this C3 homologation requires suitable methods for the generation of the acetylide anion that are compatible with both the conjugated ester and the electrophilic partner. Recent advances include catalytic procedures for the in situ generation of these acetylides in the presence of suitable electrophiles. Whereas the organometallic methods have brought stereoselectivity to these reactions, the organocatalytic methods laid the ground for new efficient domino processes that generate complexity. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
Publisher version (URL)http://dx.doi.org/10.1002/anie.200801987
Identifiersissn: 1433-7851
Appears in Collections:(IPNA) Artículos
Files in This Item:
File Description SizeFormat 
Acetylides-Garcia_Tellado.pdf7 MBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.