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Title

Microwave-assisted diversity-oriented domino synthesis of functionalized nicotinic acid derivatives

AuthorsTejedor, David ; Méndez-Abt, Gabriela ; García-Tellado, Fernando
KeywordsDomino reactions
Electrocyclic reactions
Microwave chemistry
Nitrogen heterocycles
Nicotinic acid
Issue Date22-Oct-2010
PublisherJohn Wiley & Sons
CitationEuropean Journal of Organic Chemistry: 6582-6587 (2010)
AbstractThe microwave-assisted diversity-oriented domino synthesis of functionalized alkyl nicotinates from propargyl vinyl ethers is described. The domino manifold comprises a complex network of reactions involving at least five distinct chemical steps. The obtained alkyl nicotinates incorporate two diversity points at the ring and one ester functionality as convenient handles for further elaboration. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publisher version (URL)http://dx.doi.org/10.1002/ejoc.201001067
URIhttp://hdl.handle.net/10261/132586
DOI10.1002/ejoc.201001067
Identifiersissn: 1434-193X
e-issn: 1099-0690
Appears in Collections:(IPNA) Artículos
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