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Title

A diversity-oriented strategy for the construction of tetrasubstituted pyrroles via coupled domino processes

AuthorsTejedor, David ; González-Cruz, David ; Marrero-Tellado, José Juan ; García-Tellado, Fernando ; López Rodríguez, Matías
Issue Date19-Jun-2004
PublisherAmerican Chemical Society
CitationJournal of the American Chemical Society 126(27): 8390-8391 (2004)
AbstractA new microwave-assisted rearrangement of 1,3-oxazolidines scaffolds is the basis for a new, metal-free, direct, and modular construction of tetrasubstituted pyrroles from terminal-conjugated alkynes, aldehydes, and primary amines. This new reaction manifold entails two linked domino processes in a one-pot manner with both atom- and bond-efficiency and under very simple and environment-friendly experimental conditions.
Description2 pages, 1 table, 1 scheme.-- PMID: 15237991 [PubMed].-- Printed version published Jul 14, 2004.
Supporting information available: Crystallographic data of 3n (CIF) and experimental preparations for 1a-p, 3a-p, 5, and 6 (PDF).-- Available at: http://pubs.acs.org/doi/suppl/10.1021/ja047396p
Publisher version (URL)http://dx.doi.org/10.1021/ja047396p
URIhttp://hdl.handle.net/10261/13234
DOI10.1021/ja047396p
ISSN0002-7863
Appears in Collections:(IPNA) Artículos
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