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Title

Amino acid-based surfactants: New antimicrobial agents

AuthorsPinazo, Aurora; Manresa, Maria Àngels; Marqués, Ana María; Bustelo, M.; Espuny, María Josè; Pérez, Lourdes F.
KeywordsAggregation
Amino acid-based surfactants
Antimicrobial activity
Cytotoxicity
Mode of action
Issue DateFeb-2016
PublisherElsevier
CitationAdvances in Colloid and Interface Science 228: 17-39(2016)
AbstractThe rapid increase of drug resistant bacteria makes necessary the development of new antimicrobial agents. Synthetic amino acid-based surfactants constitute a promising alternative to conventional antimicrobial compounds given that they can be prepared from renewable raw materials. In this review, we discuss the structural features that promote antimicrobial activity of amino acid-based surfactants. Monocatenary, dicatenary and gemini surfactants that contain different amino acids on the polar head and show activity against bacteria are revised. The synthesis and basic physico-chemical properties have also been included. © 2015 Elsevier B.V. All rights reserved.
Publisher version (URL)http://dx.doi.org/10.1016/j.cis.2015.11.007
URIhttp://hdl.handle.net/10261/131666
DOI10.1016/j.cis.2015.11.007
Appears in Collections:(IQAC) Artículos
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