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dc.contributor.authorBračič, Matejes_ES
dc.contributor.authorPérez, Lourdes F.es_ES
dc.contributor.authorMartinez-Pardo, Rosa Infantees_ES
dc.contributor.authorKogej, Ksenijaes_ES
dc.contributor.authorHribernik, Silvoes_ES
dc.contributor.authorŠauperl, Oliveraes_ES
dc.contributor.authorFras Zemljič, Lidijaes_ES
dc.identifier.citationCellulose 21(4): 2647-2663(2014)es_ES
dc.description.abstractIn this investigation, a novel coating for viscose fabric surface modification was developed using a synergistic formulation between a natural antimicrobial cationic surfactant from lysine (MKM) and a biopolymer hyaluronic acid (HA). The interaction between MKM and HA in aqueous solutions, as well as the interactions between their synergistic formulation (HA-MKM) and viscose fabric (CV) were studied using pH-potentiometric titrations', turbidity measurements, the Kjeldahl method for the determination of nitrogen amounts, attenuated total reflectance fourier transform infrared spectroscopy, and scanning electron microscopy. The hydrophilic and antimicrobial properties of the functionalised CV were examined in order to evaluate its usages for medical applications. The results of the interaction studies showed that MKM and HA interact with each other by forming a precipitate when the binding sites of HA are saturated. The precipitate has a slightly positive charge at neutral pH due to excess binding of the MKM to HA. The excess positive charge was also detected on CV coated with HA-MKM. This was proven to be very beneficial for the antimicrobial properties of the functionalised CV. The antimicrobial tests showed exceptional antimicrobial activity of the functionalised CV against Escherichia Coli, Staphylococcus Aureus, Streptococcus Agalactiae, Candida Albicans, and Candida Glabrata, making the CV fabric highly interesting for potential use in medicine. © 2014 Springer Science+Business Media Dordrecht.es_ES
dc.description.sponsorshipThe financial support of Savatech d.o.o., Industrial rubber products and tyres is gratefully acknowledged. The authors also acknowledge the financial support from the Ministry of Education, Science and Sport of the Republic of Slovenia through the program P2 0118 as well l as ARRS project L2-4060 .and the financial support from Spanish Plan National I+D+I MAT2012-38047-C02-02.es_ES
dc.subjectAntimicrobial activityes_ES
dc.subjectHyaluronic acides_ES
dc.subjectNatural cationic surfactantes_ES
dc.subjectpH-potentiometric titrationes_ES
dc.titleA novel synergistic formulation between a cationic surfactant from lysine and hyaluronic acid as an antimicrobial coating for advanced cellulose materialses_ES
dc.description.peerreviewedPeer reviewedes_ES
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