Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/128681
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Colomer, Aurora | es_ES |
dc.contributor.author | Pérez, Lourdes | es_ES |
dc.contributor.author | Pons Pons, Ramón | es_ES |
dc.contributor.author | Infante, María Rosa | es_ES |
dc.contributor.author | Pérez-Clos, Daniel | es_ES |
dc.contributor.author | Manresa, Ángeles | es_ES |
dc.contributor.author | Espuny, María José | es_ES |
dc.contributor.author | Pinazo Gassol, Aurora | es_ES |
dc.date.accessioned | 2016-02-04T09:46:00Z | - |
dc.date.available | 2016-02-04T09:46:00Z | - |
dc.date.issued | 2013-06-25 | - |
dc.identifier.citation | Langmuir 29(25): 7912-7921 (2013) | es_ES |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | http://hdl.handle.net/10261/128681 | - |
dc.description.abstract | In this paper, we report studies which aim to elucidate the mechanisms involved in the antimicrobial activity of three cationic lysine-based surfactants: LLM, LALM, and C6 (LL)2. To this end, a simple membrane model (i.e., 1,2-dipalmitoyl-sn-phosphatidylcholine, DPPC) was used to explore the monolayer properties at the air/liquid interface. Compression π-A isotherms of mixtures of DPPC/lysine surfactants at different pH showed an expansion of the DPPC monolayer, suggesting cationic lysine surfactant/DPPC interactions, which strongly depend on surfactant structure and hydrophobic interactions. Antimicrobial activity of the three surfactants has also been assessed with transmission electron microscopy, observing the effects on Staphylococcus aureus and Escherichia coli. The three surfactants caused various kinds of damage to the bacteria tested, such as structural alterations, leakage of internal material, and cell destruction. | es_ES |
dc.description.sponsorship | Authors have been supported by the CICYT Spanish Research Agency under the projects CTQ2009-14151-C02-01 and CTQ2010-14897 and by AGAUR Research Agency of the Generalitat de Catalunya under the project 2009 SRG 246 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Chemical Society | es_ES |
dc.relation.isversionof | Postprint | es_ES |
dc.rights | openAccess | es_ES |
dc.subject | Anti-microbial activity | es_ES |
dc.subject | Cell destruction | es_ES |
dc.subject | Hydrophobic interactions | es_ES |
dc.subject | Membrane models | es_ES |
dc.subject | Mixed monolayers | es_ES |
dc.subject | Staphylococcus aureus | es_ES |
dc.subject | Structural alterations | es_ES |
dc.subject | Surfactant structure | es_ES |
dc.title | Mixed monolayer of DPPC and lysine-based cationic surfactants: An investigation into the antimicrobial activity | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1021/la401092j | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | https://doi.org/10.1021/la401092j | es_ES |
dc.identifier.e-issn | 1520-5827 | - |
dc.rights.license | http://www.sherpa.ac.uk/romeo/issn/0743-7463/ | es_ES |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | es_ES |
dc.relation.csic | Sí | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
Aparece en las colecciones: | (IQAC) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
RP_Langmuir2013.pdf | 2,18 MB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
26
checked on 03-abr-2024
WEB OF SCIENCETM
Citations
22
checked on 19-feb-2024
Page view(s)
187
checked on 22-abr-2024
Download(s)
303
checked on 22-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.