English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/128625
Compartir / Impacto:
Add this article to your Mendeley library MendeleyBASE
Citado 7 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)

Sexual selection on protamine and transition nuclear protein expression in mouse species

Autor Lüke, Lena; Campbell, Polly; Varea-Sánchez, María; Nachman, Michael W.; Roldán, Eduardo R. S.
Palabras clave Sexual selection
Transition nuclear protein
Sperm competition
Fecha de publicación 26-mar-2014
EditorRoyal Society (Great Britain)
Citación Proceedings of the Royal Society of London - B 281(1783): 20133359 (2014)
ResumenPost-copulatory sexual selection in the form of sperm competition is known to influence the evolution of male reproductive proteins in mammals. The relationship between sperm competition and regulatory evolution, however, remains to be explored. Protamines and transition nuclear proteins are involved in the condensation of sperm chromatin and are expected to affect the shape of the sperm head. A hydrodynamically efficient head allows for fast swimming velocity and, therefore, more competitive sperm. Previous comparative studies in rodents have documented a significant association between the level of sperm competition (as measured by relative testes mass) and DNA sequence evolution in both the coding and promoter sequences of protamine 2. Here,we investigate the influence of sexual selection on protamine and transition nuclear protein mRNA expression in the testes of eight mouse species that differ widely in levels of sperm competition.We also examined the relationship between relative gene expression levels and sperm head shape, assessed using geometric morphometrics. We found that species with higher levels of sperm competition express less protamine 2 in relation to protamine 1 and transition nuclear proteins. Moreover, therewas a significant association between relative protamine 2 expression and sperm head shape. Reduction in the relative abundance of protamine 2 may increase the competitive ability of sperm in mice, possibly by affecting sperm head shape. Changes in gene regulatory sequences thus seem to be the basis of the evolutionary response to sexual selection in these proteins. © 2014 The Author(s) Published by the Royal Society. All rights reserved.
URI http://hdl.handle.net/10261/128625
Identificadoresdoi: 10.1098/rspb.2013.3359
e-issn: 1471-2954
issn: 0962-8452
Aparece en las colecciones: (MNCN) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
ProcRSocLondon B281(1783) 20133359 (2014) POSTPRINT.pdf492,2 kBAdobe PDFVista previa
Mostrar el registro completo

NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.