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dc.contributor.authorMartín, Verónica-
dc.contributor.authorMavian, Carla-
dc.contributor.authorLópez-Bueno, Alberto-
dc.contributor.authorMolina, Antonio de-
dc.contributor.authorDíaz, Eduardo-
dc.contributor.authorAndrés, Germán-
dc.contributor.authorAlcamí, Antonio-
dc.contributor.authorAlejo, Alí-
dc.date.accessioned2015-11-03T11:42:50Z-
dc.date.available2015-11-03T11:42:50Z-
dc.date.issued2015-10-15-
dc.identifierdoi: 10.1128/JVI.01580-15-
dc.identifierissn: 1098-5514-
dc.identifier.citationJournal of Virology 89(20): 10702- 10706 (2015)-
dc.identifier.urihttp://hdl.handle.net/10261/124360-
dc.description.abstractAmphibian-like ranaviruses include pathogens of fish, amphibians, and reptiles that have recently evolved from a fish-infecting ancestor. The molecular determinants of host range and virulence in this group are largely unknown, and currently fish infection models are lacking. We show that European sheatfish virus (ESV) can productively infect zebrafish, causing a lethal pathology, and describe a method for the generation of recombinant ESV, establishing a useful model for the study of fish ranavirus infections.-
dc.description.sponsorshipThis work was supported by grant AGL 2009-08711 from the Spanish Ministerio de Ciencia e Innovación and grant AGL2013-48998-C2-2-R from the Ministerio de Economía y Competitividad. G.A. was supported by the Amarouto Program for senior researchers from the Comunidad Autónoma de Madrid. A.L.B. and V.M. are holders of RyC-2010-06300 and RyC-2010-06516 Ramón y Cajal fellowships from the Spanish Ministerio de Ciencia e Innovación.-
dc.publisherAmerican Society for Microbiology-
dc.relation.isversionofPublisher's version-
dc.rightsopenAccess-
dc.titleEstablishment of a zebrafish infection model for the study of wild-type and recombinant European sheatfish virus-
dc.typeartículo-
dc.identifier.doi10.1128/JVI.01580-15-
dc.date.updated2015-11-03T11:42:51Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.contributor.funderMinisterio de Ciencia e Innovación (España)-
dc.contributor.funderMinisterio de Economía y Competitividad (España)-
dc.contributor.funderComunidad de Madrid-
dc.relation.csic-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004837es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003329es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/100012818es_ES
dc.identifier.pmid26246565-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.grantfulltextopen-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
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