English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/123887
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

DC FieldValueLanguage
dc.contributor.authorSánchez-Herrero, Ernesto-
dc.date.accessioned2015-10-27T09:42:16Z-
dc.date.available2015-10-27T09:42:16Z-
dc.date.issued2013-
dc.identifierdoi: 10.1155/2013/738257-
dc.identifierissn: 2090-908X-
dc.identifier.citationScientifica 2013: 738257 (2013)-
dc.identifier.urihttp://hdl.handle.net/10261/123887-
dc.description.abstractHox genes are a group of genes that specify structures along the anteroposterior axis in bilaterians. Although in many cases they do so by modifying a homologous structure with a different (or no) Hox input, there are also examples of Hox genes constructing new organs with no homology in other regions of the body. Hox genes determine structures though the regulation of targets implementing cellular functions and by coordinating cell behavior. The genetic organization to construct or modify a certain organ involves both a genetic cascade through intermediate transcription factors and a direct regulation of targets carrying out cellular functions. In this review I discuss new data from genome-wide techniques, as well as previous genetic and developmental information, to describe some examples of Hox regulation of different cell functions. I also discuss the organization of genetic cascades leading to the development of new organs, mainly using Drosophila melanogaster as the model to analyze Hox function-
dc.publisherHindawi Publishing Corporation-
dc.relation.isversionofPublisher's version-
dc.rightsopenAccess-
dc.titleHox targets and cellular functions-
dc.typeartículo-
dc.identifier.doi10.1155/2013/738257-
dc.date.updated2015-10-27T09:42:17Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.rights.licensehttp://creativecommons.org/licenses/by/3.0/es/-
dc.relation.csic-
Appears in Collections:(CBM) Artículos
Files in This Item:
File Description SizeFormat 
Ernesto_Sanchez_Herrero_hox_targets.pdf1,43 MBAdobe PDFThumbnail
View/Open
Show simple item record
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.