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Title

Contributions of an orthopteran to the understanding of neuronal pathfinding

AuthorsSánchez, Diego; Ganfornina, M. D. ; Bastiani, Michael J.
KeywordsAxon guidance
Cell-surface molecule
Grasshopper
Growth cone
Orthoptera
Pathfinding
Issue Date1995
PublisherNature Publishing Group
CitationImmunology and Cell Biology 73(6): 565-574 (1995)
AbstractDuring the development of the nervous system neurons extend axons through a complex embryonic environment. To find a correct target, often located at a long distance, the neuronal growth cones travel along highly specific and stereotyped pathways. Proper neuronal pathfinding is thought to be accomplished by the specific interaction of receptors on the neuronal surface with molecular cues in the environment. We review the information obtained in an invertebrate model system, the grasshopper embryo, about the specific role of the cell surface in wiring the nervous system.
URIhttp://hdl.handle.net/10261/122913
DOI10.1038/icb.1995.90
ISSN0818-9641
E-ISSN1440-1711
Appears in Collections:(IBGM) Artículos
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