English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/122794
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


NAPPA as a real new method for protein microarray generation

AutorDíez, Paula; González González, María; Lourido, Lucía; Dégano, Rosa M.; Ibarrola, Nieves ; Casado-Vela, Juan; LaBaer, Joshua; Fuentes, Manuel
Palabras claveProtein microarray
High-throughput screening
Protein-protein interaction
Microarray generation
Fecha de publicación2015
EditorMultidisciplinary Digital Publishing Institute
CitaciónMicroarrays 4(2): 214-227 (2015)
ResumenNucleic Acid Programmable Protein Arrays (NAPPA) have emerged as a powerful and innovative technology for the screening of biomarkers and the study of protein-protein interactions, among others possible applications. The principal advantages are the high specificity and sensitivity that this platform offers. Moreover, compared to conventional protein microarrays, NAPPA technology avoids the necessity of protein purification, which is expensive and time-consuming, by substituting expression in situ with an in vitro transcription/translation kit. In summary, NAPPA arrays have been broadly employed in different studies improving knowledge about diseases and responses to treatments. Here, we review the principal advances and applications performed using this platform during the last years.
DescripciónThis is an open access article distributed under the Creative Commons Attribution License.-- This article belongs to the Special Issue "New and Old Technologies for Generation of Microarrays".
Versión del editorhttp://dx.doi.org/10.3390/microarrays4020214
Aparece en las colecciones: (IBMCC) Artículos
(CNB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
NAPPA as a Real.pdf1,06 MBAdobe PDFVista previa
Mostrar el registro completo

Artículos relacionados:

NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.